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neptal 3% ampoule

https://mhc.andornot.com/en/permalink/artifact3891
Dates
1896
circa 1896
Collection
Dr. Charles H. Bird / Dr. Godfrey Bird Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Other
Accession Number
997037481
Description
An ampoule that is a long, liquid-filled cylindrical glass tube that is closed on both ends and has a flat bottom; the main tube has straight sides and tapers to a thin teardrop-shaped tip with a rounded end.
  1 image  
Accession Number
997037481
Collection
Dr. Charles H. Bird / Dr. Godfrey Bird Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Other
MeSH Heading
Adrenergic beta-Antagonists
Drug Packaging -- instrumentation
MM= Drug Packaging -- container -- ampoule
Description
An ampoule that is a long, liquid-filled cylindrical glass tube that is closed on both ends and has a flat bottom; the main tube has straight sides and tapers to a thin teardrop-shaped tip with a rounded end.
Number Of Parts
1
Provenance
Used by either Dr. H. Godfrey Bird or Dr. C.H. Bird of Gananoque, Ontario.
Maker
Poulenc Freres
Site Made (City)
Montreal
Site Made (State)
Quebec
Site Made (Country)
Canada
Dates
1896
circa 1896
Date Remarks
This date marks the beginning of the Bird medical practice.
Material
glass: clear
Inscriptions
Ampoule reads, "NEPTAL 3% // Ampoule 1½ cc. // POULENC FRERES // MONTREAL"
Permanent Location
Storage Room 0010
0010-A3-3 Box 1
Dimension Notes
Length 7.4 cm x Diam. 1.1 cm
Condition Remarks
No chipping or spotting apparent
Copy Type
Original
Reference Comments
Internet: - https://doi.org/10.1136/bmj.2.4526.530 - https://pdfs.semanticscholar.org/add9/4317fdd44f704cc2cf0cd045f2e1c65a42ab.pdf - https://www.ndrugs.com/?s=neptal
Research Facts
This can be taken both intravenously or with an intramuscular injection. It works as a diuretic (increases urine production) and helps with hypertension. It is effective, but very dangerous as it contains mercury (mercurial diuretic).
Images
Less detail
Dates
1960
1970
circa 1960-1970
Collection
Rockwood / Kingston Psychiatric Hospital / Providence Continuing Care Centre Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Psychiatry
Accession Number
000003095
Description
Sample packet of 6 Tofranazine capsules, which consists of 6 ivory-coloured capsules in plastic packets attached to a heavy paper information packet; the packet is made of a single piece of heavy printed paper with the capsules attached to the front right side and then folded into three equal parts…
  1 image  
Accession Number
000003095
Collection
Rockwood / Kingston Psychiatric Hospital / Providence Continuing Care Centre Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Psychiatry
MeSH Heading
Anxiety -- drug therapy
Depression -- drug therapy
Antidepressant Agents
MM= Drugs -- anti-depressant
Description
Sample packet of 6 Tofranazine capsules, which consists of 6 ivory-coloured capsules in plastic packets attached to a heavy paper information packet; the packet is made of a single piece of heavy printed paper with the capsules attached to the front right side and then folded into three equal parts to cover the capsules on both sides; the paper has printed information on the medication and an illustration on the front.
Number Of Parts
1
Provenance
Used at the Kingston Psychiatric Hospital.
Maker
Geigy (Canada) Limited; Geigy Pharmaceuticals
Site Made (City)
Montreal
Site Made (State)
Quebec
Site Made (Country)
Canada
Dates
1960
1970
circa 1960-1970
Material
capsules: ivory
plastic: clear
paper: off-white; red
Inscriptions
The front of the packet reads, "Tofranazine Geigy // alleviates anxiety . . . // dispels depression"; the back of the packet has information on side effects and reads, "Geigy Pharmaceuticals // Division of Geigy (Canada) Limited // Montreal // L - 1595 Printed in Canada"; information in the booklet includes, "Indication // Dosage // Availability // Precautions // Directions"
Permanent Location
Storage Room 0010
0010-A2-7
Dimension Notes
Length 12.4 cm x Width 8.8 cm x Depth 0.5 cm (folded)
Condition Remarks
The sample is unused; the front of the packet shows minor wear, but is complete and fully legible; two of the capsules have been crushed and powder is leaking out, but they are contained within the plastic packet.
Copy Type
Original
Research Facts
Medication used to alleviate anxiety and dispel depression; sample given out by Geigy Pharmaceuticals.
On Tuesday, September 18, 1962, a Canadian trademark registration was filed for TOFRANAZINE by CIBA-GEIGY CANADA LTD. - CIBA- 205 BOUCHARD BOULEVARD, DORVAL 780, QUEBEC, CANADA . The Canadian IP office has given the trademark application number of 264964.
Exhibit History
On display “History of Psychiatry” at the Royal College of Physicians and Surgeons of Canada, Ottawa L-2018-2; 20 March 2018 – 31 Dec 2019
On exhibit at the Pump House Museum, Kingston, Ontario L-2017-4; 24 April 2017 – 28 Aug 2017.
Images
Less detail
Dates
1960
1970
circa 1960-1970
Collection
Rockwood / Kingston Psychiatric Hospital / Providence Continuing Care Centre Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Psychiatry
Accession Number
000003096
Description
Physician's sample packet of six green Parstelin tablets in clear plastic blister pack glued at the bottom to a 29.0 cm long folded paper information sheet; once the paper is folded five times around the tablets a package is created; printing on both sides; section where tablets are attached is per…
  3 images  
Accession Number
000003096
Collection
Rockwood / Kingston Psychiatric Hospital / Providence Continuing Care Centre Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Psychiatry
MeSH Heading
Anxiety -- drug therapy
Depression -- drug therapy
Antidepressant Agents
MM= Drugs -- anti-depressant
Description
Physician's sample packet of six green Parstelin tablets in clear plastic blister pack glued at the bottom to a 29.0 cm long folded paper information sheet; once the paper is folded five times around the tablets a package is created; printing on both sides; section where tablets are attached is perforated to tear off as a prescription; tablets have initials SKF on one side.
Number Of Parts
1
Provenance
Used at the Kingston Psychiatric Hospital.
Maker
Smith Kline & French
Site Made (City)
Montreal
Site Made (State)
Quebec
Site Made (Country)
Canada
Dates
1960
1970
circa 1960-1970
Material
paper: cream
ink: green, blue
plastic: transparent
tablets: green
Inscriptions
Front of packet: "Parstelin* // (combination of Parnate* and Stelazine*) // dual-action therapy to relieve // CO-EXISTENT DEPRESSION AND ANXIETY // Smith Kline & French . Montreal 9 // * Reg. Can. T.M. Off. // 6 Tablets Physician's Sample // 'Parstelin' is a combination of two outstandingly // useful psychotherapeutic agents deevloped by SK&F // research - 'Parnate' and 'Stelazine'. // FORMULA // INDICASTIONS // DOSAGE: Uusual dosage is one tablet twice daily - morn- // ing and afternoon.The first signs of improvement are // frequently seen within one to three days and usually // witin a week. If an increase in dosage is required, one // tablet shoudl be added in the morning dose after the first // week of therapy. // Pat. No. 616,537 (1961) Pat. No. 612,204 (1961) // PRECAUTIONS // CONTRAINDICATION // HOW SUPPLIED // CG : 336 // LOT D 1566"
Permanent Location
Storage Room 0010
0010-A3
Dimension Notes
open flat = Length 29.0 cm x Width 8.4 cm x Depth 0.3 cm
Condition Remarks
Shows minor wear on front and back; tablets are complete and undamaged; all printing is fully legible
Copy Type
Original
Reference Types
Internet
Reference Comments
Wikipedia
Research Facts
Tranylcypromine / trifluoperazine (brand names Parstelin, Parmodalin, Jatrosom N, Stelapar) is a combination formulation of the monoamine oxidase inhibitor antidepressant drug tranylcypromine and the typical antipsychotic drug trifluoperazine that has been used in the treatment of major depressive disorder. It contains 10 mg tranylcypromine and 1 mg trifluoperazine.The drug has been in clinical use since at least 1961.It is still available in Italy with the name of Parmodalin.
Parstelin A brand name for a mixture of TRANYLCYPROMINE and TRIFLUOPERAZINE. Product development discontinued.
Exhibit History
On exhibit at Musée de la civilisation de Québec 13 March 2017 - 30 March 2018
Images
Less detail