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Antikamnia & Codeine tablets

https://mhc.andornot.com/en/permalink/artifact14637
Dates
1890
1910
circa 1890 - 1910
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Pain
Accession Number
016022043
Description
Rectangular hinged metal pill container with company name and directions typed on the lid and bottom of container.
  2 images  
Accession Number
016022043
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Pain
MeSH Heading
Pain -- drug therapy
Description
Rectangular hinged metal pill container with company name and directions typed on the lid and bottom of container.
Number Of Parts
1
Maker
Antikamnia Chemical Company
Site Made (City)
St. Louis
Site Made (State)
Missouri
Site Made (Country)
United States of America
Dates
1890
1910
circa 1890 - 1910
Material
metal: silver, black, cream
Inscriptions
Printed on top of container: “PHYSICIAN SAMPLE // 5 Gr. // ANTIKAMNIA & CODEINE // TABLETS // 4 ¾ Gr ANTIKAMNIA. ¼ Gr SULPH CODEINE // REGISTERED SEPT 3 1890 // MANUFACTURED IN THE UNITED STATES OF AMERICA // BY THE ANTIKAMNIA CHEMICAL CO. // ST. LOUIS. MO,. U.S.A. // British Depot: 46 Kalborn Viaduct, London E.C” directions printed on bottom
Permanent Location
Storage Room 0010
0010-A2-4 Row E
Temporary Location
On travelling exhibit ‘Unmasking Influenza’ Ottawa L-2019-3 30 April 2019-31 Dec 2022.
Length
4.4
Width
3.5
Depth
0.5
Unit Of Measure
centimeters
Condition Remarks
Minor chiping of paint off of container; does not open; can hear something inside.
Copy Type
original
Reference Types
Internet
Reference Comments
Anitikamnian Chemical Company. Window Through Time
The Deadly Pain Medicine Sold by Skeletons. Bess Lovejoy
Research Facts
Antikamnia varied over time, its principal ingredient was always acetanilide, a coal tar derivative. Acetanilide had the unfortunate side effect of producing cyanosis, meaning it turned extremities blue from a lack of oxygen. Deaths related to the ingredient were reported as early as 1891.
The medicine was never patented and wasn’t a prescription drug, the Anitikamnia Drug Company marketed the tablets aggressively through direct mailing and promotional products to doctors in the hope that they would be persuaded to recommend it to their patients.
The tablets were marketed to treat "La Grippe, Influenza and all Grippal Conditions, Pneumonia, Bronchitis, Deep Seated Coughs, Neuroses of the Larynx etc, etc”. It was also handy to be taken as a preventative before participating in sports or even going out shopping.
Half a century later Julius Axelrod discovered that what acetanilide produces when metabolised is paracetamol, we take this medication today and it is called Tylenol. So, Antikamnia may just have been effective as a pain-killer.
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Instantine-Plus analgesic tablets with codeine

https://mhc.andornot.com/en/permalink/artifact13372
Dates
1950
1970
circa 1950-1970
Collection
Dr. Ralph and Mrs. Olga Crawford Canadian Dental Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Pain
Accession Number
010020250
Description
Instantine-Plus tablet tin with clasp closure at front; rectangular silver metal tin, enamelled in blue and white; product information, directions, manufacturer's information printed with blue and red enamel in English and French on front and back; extra information printed in blue on underside of …
  3 images  
Accession Number
010020250
Collection
Dr. Ralph and Mrs. Olga Crawford Canadian Dental Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Pain
MeSH Heading
Analgesics
Pain -- drug therapy
Drugs, Non-Prescription
MM= Drug Packaging -- container -- tin
Description
Instantine-Plus tablet tin with clasp closure at front; rectangular silver metal tin, enamelled in blue and white; product information, directions, manufacturer's information printed with blue and red enamel in English and French on front and back; extra information printed in blue on underside of lid; tin contains two white tablets, three crystallized pink tablets, six brown crystallized tablets
Number Of Parts
1
Provenance
Transfer from the Dental Canada Fund; previously housed in the Dentistry Canada Museum (Ottawa)
Maker
The Bayer Company Ltd.
Site Made (City)
Aurora
Site Made (State)
Ontario
Site Made (Country)
Canada
Dates
1950
1970
circa 1950-1970
Date Remarks
Based on packaging
Material
metal: silver
enamel: black, red, yellow
Inscriptions
Printed on front: "N // Instantine-Plus // WITH CODEINE // TRADE MARKS REG. // FAST PROLONGED RELIEF FROM PAIN // 12 TABLETS // PRESS HERE"; printed inside lid: "INDICATIONS: Headache, colds, feverish conditions, neuralgia, // and rheumatic pains. Follow directions on bottom of tin. // A BAYER // PRODUCT // Instantine-Plus // UN PRODUIT // BAYER // MARQUE DEPOSEE // SOULAGEMENT RAPIDE ET PROLONGE DE LA DOULEUR CAUSEE PAR // Les maux de tete, rhumes, etats febriles, nevralgies, et douleurs // rhumatismales. Suivez le mode d'emploi sur le fond de la boite."
Permanent Location
Storage Room 0010
0010-A2-4 Row G
Dimension Notes
Length 8.1 cm x Width 3.1 cm x Depth 0.6 cm
Condition Remarks
Enamel faded on tin, especially around edges; tablets are brown and crystallized
Copy Type
Original
Reference Types
JPG
Reference Comments
CD #10
Research Facts
Dr Ralph and Mrs Olga Crawford donated their extensive Canadian dental collection to the DCF to create the museum in 1997; further donations were received while Dr Crawford was Curator Emeritus at the Dental Canada Museum until its closure in 2008
Images
Less detail