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measles vaccine kit

https://mhc.andornot.com/en/permalink/artifact4044
Dates
1968
circa 1968
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001249 a-g
Description
A styrofoam container (a) consisting of two moulded pieces of styrofoam held together by the label; inside are five cylindrical glass ampoules (b-f) with icicle-shaped melted glass seals containing the vaccine and one glass vial (g) stopped with a rubber stopper and sealed with a metal ring around …
  4 images  
Accession Number
000001249 a-g
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Measles -- prevention & control
Measles Vaccine
Vaccination
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- ampoule
Description
A styrofoam container (a) consisting of two moulded pieces of styrofoam held together by the label; inside are five cylindrical glass ampoules (b-f) with icicle-shaped melted glass seals containing the vaccine and one glass vial (g) stopped with a rubber stopper and sealed with a metal ring around the lip containing a diluent.
Number Of Parts
7
Part Names
a - box - Size: Length 13.9 cm x Width 8.3 cm x Depth 3.0 cm
b - ampoule - Size: Length 5.8 cm x Diam. 1.1 cm
c - ampoule - Size: Length 5.8 cm x Diam. 1.1 cm
d - ampoule - Size: Length 5.8 cm x Diam. 1.1 cm
e - ampoule - Size: Length 5.8 cm x Diam. 1.1 cm
f - ampoule - Size: Length 5.8 cm x Diam. 1.1 cm
g - vial - Size: Length 4.1 cm x Diam. 2.1 cm
Provenance
Collected by Parke-Davis
Maker
Philips Roxane, Inc.
Site Made (City)
St. Joseph
Site Made (State)
Missouri
Site Made (Country)
United States of America
Dates
1968
circa 1968
Date Remarks
Earliest expiry date
Material
styrofoam: white
paper: white; blue; black
glass: clear; blue
rubber: yellow
metal: silver
Inscriptions
(a) Top: "5 DOSES Bio. 49 // MEASLES VIRUS VACCINE, // LIVE, ATTENUATED // C // Contains 5 one-dose ampoules of attenuated Edmonston strain vaccine grown on // tissue cultures of canine renal cells and one 4.5 cc. vial of diluent for preparing solu- // tion for injection. Diluent contains 0.05% methylparaben and 0.005% propylparaben // as preservatives. // Prepare solution for injection by slowly adding 0.7 cc. diluent to contents of // ampoule. Gently agitate and allow a few seconds for the contents to dissolve. // DOSE – A single injection of 0.5 cc. of solution prepared as above, administered // subcutaneously into the upper arm; or subcutaneously or intramuscularly into the // upper, outer quadrant of the buttocks. For coadministration of gamma globulin, // see package insert. // Administration to infants under nine months of age is not recommended. // See package insert for contraindications and precautions. // Expiration Date: [printed] // Oct. 15, 1969 [stamped] // Lot No. [printed] // PD804B [stamped] // Stock 4-49-1-70 // Distributed by // PARKE, DAVIS & CO. DETROIT, MICH., U.S.A."; front: "Each dose contains not less than 1000 TCid50 ["50" subscr.] of measles virus vaccine as compared // to U.S. NIH measles virus reference standard, not more than 33 mcg. dihydrostrep- // tomycin sulfate and 17 units of polymyxin B sulfate. // CUT ON DOTTED LINE // Store at temperature between 2° and 8° C (35.6° and 46.4° F.). // Storage at freezing temperature not required. // Protect vaccine from prolonged exposure to direct sunlight."; back: "Manufactured by // PHILIPS ROXANE, INC. ST JOSEPH, MO., U.S.A. // U.S. Licence 376. Canadian Licence 127"; (b-e) "1 DOSE Bio. 49 // MEASLES VIRUS VACCINE, // LIVE, ATTENUATED // 1000 TCID50 ["50" subscr.] // See insert. // US. Licence 376 // Mfd. by Philips Roxane, Inc. // St. Joseph, Mo., U.S.A. // Dist. by Parke, Davis & Co. // Detroit, Mich., U.S.A.// LOT PD 804B // Exp. )ct. 15-69 [stamped]"; (f) same printed text as (b-e) followed by "LOT PD619-1 // Exp. Aug. 24-68"; (g) "4.5 CC. // DILUENT FOR MEASLES VIRUS // VACCINE, LIVE, ATTENUATED // Mfd. by Philips Roxane, Inc. // St. Joseph, Mo., U.S.A. // Dist. by Parke, Davis & Co. // Detroit, Mich., U.S.A. // Contains 0.05% methylparaben and // 0.005% propylpara- // ben as preservatives. // LOT 7404D [stamped]"
Permanent Location
Storage Room 0010
0010-A3-5 Row B
Temporary Location
On exhibit at City of Ottawa - Public Health L-2016-3 14 Mar 2016 – 31 Dec 2018
Condition Remarks
Label is yellowing, dirty; some dents in styrofoam; labels on ampoules and vial are yellowing.
Copy Type
Original
Exhibit History
May 24 - Sept. 13, 2001: Agnes Etherington Art Centre Museopathy exhibit
Images
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diphtheria-tetanus-pertussis vaccine

https://mhc.andornot.com/en/permalink/artifact4298
Dates
1956
circa 1956
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001472 a-c
Description
A cylindrical glass vial (b) inside a cardboard box (a) with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded over the neck and lip; vial has a paper label on front and sides and is half full of liquid; box has a round fluorescent orange sticker on the …
  5 images  
Accession Number
000001472 a-c
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Diphtheria Toxoid -- therapeutic use
Vaccination
Tetanus Toxoid -- therapeutic use
Pertussis Vaccine -- therapeutic use
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
A cylindrical glass vial (b) inside a cardboard box (a) with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded over the neck and lip; vial has a paper label on front and sides and is half full of liquid; box has a round fluorescent orange sticker on the right side and a rectangular white sticker on the bottom
Number Of Parts
3
Part Names
a - box - Size: Length 4.7 cm x Width 2.0 cm x Depth 2.2 cm
b - vial - Size: Length 3.5 cm x Diam. 1.7 cm
c - leaflet (unfolded) - Size: Length 15.3 cm x Width 11.0 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Co.
Site Made (City)
Detroit
Site Made (State)
Michigan
Site Made (Country)
United States of America
Dates
1956
circa 1956
Date Remarks
Based on expiry date
Material
paper: white; blue
ink: black; blue
metal: silver
cardboard: blue; white
rubber: pink
glass: clear
Inscriptions
(a) Front: "C 1.5 cc. Bio. 2091 // DIPHTHERIA - TETANUS - PERTUSSIS // ALUMINUM PHOSPHATE ADSORBED // TRIOGEN // Stock 4-2091-2 // PARKE, DAVIS & CO., DETROIT, MICH., U.S.A."; bottom: "Dosage – A complete immunizi [illeg.] // ment consists of 1.5 cc. div [illeg.] // three equal doses of 0.5 cc. each [illeg.] // at intervals of from four to six [illeg.] // See circular. // Contains 0.01% Thimeros [illeg.] // Keep at 2° to 10° C. (35° to [illeg.] // DO NOT FREEZE // SHAKE WELL BEFORE US [illeg.]"; back: "Indicated for prophylaxis against diph- // theria, tetanus and whooping cough. // U.S. Lic. No. 1 Canadian Lic. no. 1 // Expiration Date: [printed] APR-20-1956 [stamped] // Lot No. [printed] 027176 - H [stamped]"; top: "For One Complete Immunizing Treatment // DIPHTHERIA and TETANUS TOXOIDS // and PERTUSSIS VACCINE, COMBINED // ALUMINUM PHOSPHATE ADSORBED // Each 1.0 cc. contains 20,000 million killed // Phase 1 Hemophilus pertussis organisms of // proven antigenicity and adequate amounts // of Diphtheria and Tetanus Toxoids."; right side: "1.5 Bio. 2091 // [illeg.] - PERT. // Alu [illeg.] Phosphate Adsorbed. // TRIOGEN // Parke, Davis & Co."; left side: 1.5 cc. Bio. 2091 // DIPH. - TET. - PERT. // Aluminum Phosphate // Adsorbed // TRIOGEN // Parke, Davis & Co."; (b) front: "1.5 cc. Dose: 0.5 cc. Bio. 2091 // C DIPHTHERIA – TETANUS – PERTUSSIS // Aluminum Phosphate Adsorbed // TRIOGEN // Seecircular. // SHAKE WELL // U.S. License No. 1. [printed] // APR–201956 // 027176-H [stamped] // PARKE, DAVIS & CO., Detroit Mich., U.S.A. porinted]"; back: "1.0 cc. contains // 20,000 million H. // pertussis and ade- // quate Diphtheria and Tetanus // Toxoids."; bottom: "NSIA // O K // U.S.A. [embossed]"; (c) "DIPHTHERIA – TETANUS – PERTUSSIS // ALUMINUM PHOSPHATE ADSORBED // TRIOGEN // [text follows] // WHEN TO IMMUNIZE // [text follows] // DOSAGE // [text follows] // STERILIZATION OF SYRINGES AND NEEDLES // [text follows] // ADMINISTRATION // [text follows] // REACTIONS // [text follows] // RECALL OR STIMULATING DOSES // [text follows] // PACKAGES // [text follows] // REFERENCES // [text follows] // PARKE, DAVIS [logo, see sketch on accession sheet] & COMPANY // DETROIT, MICH., U.S.A. // K-67 // B-0548-F—1-15-54—50M"
Permanent Location
Storage Room 0010
0010-A3-5 Row H
Temporary Location
On display: "Vaccines and Immunization: Epidemics, Prevention, and Canadian Innovation"; Museum of Health Care, Nov. 28, 2013.
Condition Remarks
Box dented, dirty, scuffed, ink fading ; label on vial yellowing; no apparent problems with leaflet
Copy Type
Original
Reference Types
Book on internet
Reference Comments
https://books.google.ca/books?id=rfpT4uZW-D0C&printsec=frontcover#v=onepage&q&f=false
Research Facts
Triogen was later combined with the Salk polio vaccine to make Quadrigen, which proved to be toxic after experiencing temperature changes. The pertussis vaccine alone, as well as combined with those for diphtheria and tetanus, has long been controversial, and there have been cases in which it has allegedly made children very sick or caused their death.
Images
Less detail