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Dates
1975
circa 1975
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001281 a-c
Description
Cylindrical glass vial (b) stopped with a rubber stopper and sealed with a metal cap around vial neck and lip; a plastic cap is attached to the metal cap such that when the plastic cap is pulled off, the seal on the metal cap is broken; vial is in a cardboard box (a) with a paper leaflet (c)
  1 image  
Accession Number
000001281 a-c
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Viral Vaccines
Vaccination
Influenza
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
Cylindrical glass vial (b) stopped with a rubber stopper and sealed with a metal cap around vial neck and lip; a plastic cap is attached to the metal cap such that when the plastic cap is pulled off, the seal on the metal cap is broken; vial is in a cardboard box (a) with a paper leaflet (c)
Number Of Parts
3
Part Names
a - box - Size: Length 5.7 cm x Width 2.9 cm x Depth 2.9 cm
b - vial - Size: Length 4.4 cm x Diam. 2.2 cm
c - leaflet (unfolded) - Size: Length 17.6 cm x Width 10.1 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Company
Site Made (City)
Detroit
Site Made (State)
Michigan
Site Made (Country)
United States of America
Dates
1975
circa 1975
Date Remarks
Based on expiry date
Material
glass: clear
paper: white; blue; black
cardboard: white; blue
plastic: blue
metal: silver
rubber: pink
Inscriptions
(a) Front: "5 ML. Bio. 1568 // FLUOGEN® // Standardized according to the U.S. Public // Health Service requirements for the // 1973-74 season. // Stock 4-1568-1-70 // PARKE-DAVIS"; bottom: "Preservative: 0.01% thimerosal (mercury deriv.) // Polysorbate 80, USP, added during manufacture. // U.S. Licence No. 1. Canadian Licence No. 1. // Store at temperature between 2° and 8° C. // (36° and 46° F.). // FREEZING DESTROYS POTENCY // Parke, Davis & Company // Detroit, Michigan 48232 U.S.A."; back: "5 ML. Bio. 1568 // INFLUENZA VIRUS VACCINE, BIVALENT // (IMMUNIZING ANTIGEN, ETHER EXTRACTED) // C Contains no less than 1000 CCA units per human dose (0.5 // ml.) in the recommended ratio of 700 CCA units of the A // influenza virus component representative of A/England/ // 42/72 (H3N2) and 300 CCA units of the B influenza virus // component representative of B/Massachusetts/1/71. // PARKE-DAVIS"; top: "USUAL ADULT DOSE – Two intramuscular injections // of 0.5 ml. each, given at least two months apart. See // package insert. // [dose repeated in French] // Prepared from formalin-stabilized, zonally-centrifuged // antigens, ether-extracted from virus propogated in the // extraembryonic fluid of the chick embryo. // U.S. Patent No. 3,105,012"; right side: "5 ML. Bio. 1568 // FLUOGEN // Parke, Davis & Co. // Exp. Date and Lot [printed] Feb. 1, 1975 // 903033B [stamped]"; (b) front: "C // 5 ML. Bio. 1568 // INFLUENZA VIRUS VACCINE, BIVALENT // (IMMUNIZING ANTIGEN, ETHER EXTRACTED) // FLUOGEN® // Contains no less than 1000 CCA units per human dose // (0.5 ml.) in the recommended ratio of 700 CCA units of the A influenza virus component representative of A/England/ // 42/72 (H3N2) and 300 CCA units of the B influenza virus // component representative of B/Massachusetts/1/71. // Parke, Davis & Co., Detroit, Mich. 48232 U.S.A."; back: "USUAL ADULT DOSE – Two // intramuscular injections of 0.5 // ml. each, given at least two months apart. See package // inssert. // Standardized according to the // U.S. Public Health Service // requirements for the 1973-74 // season. // U.S. Lic. No. 1. // Canadian Lic. No. 1. // Exp Date and Lot [printed] // Feb. 1, 1975 // 903033B [stamped]"; bottom: "W // 83 [embossed]"; top: "FLIP // OFF [embossed]"; (c) "C // FLUOGEN® // (INFLUENZA VIRUS VACCINE, BIVALENT) // IMMUNIZING ANTIGEN, ETHER EXTRACTED // PARKE-DAVIS // DESCRIPTION // [text follows] // 121 877800 C-PO // FLUOGEN // (INFLUENZA VIRUS VACCINE, BIVALENT) // IMMUNIZING ANTIGEN, ETHER EXTRACTED // [text continues from DESCRIPTION] // INDICATIONS // [text follows] // 121 877800 2 C - PD // FLUOGEN // (INFLUENZA VIRUS VACCINE, BIVALENT) // IMMUNIZING ANTIGEN, ETHER EXTRACTED // [text continues from INDICATIONS] // CONTRAINDICATIONS // [text follows] // PRECAUTIONS // [text follows] // ADVERSE REACTIONS // [text follows] // 121 877800 3 C-PD // FLUOGEN // (INFLUENZA VIRUS VACCINE, BIVALENT) // IMMUNIZING ANTIGEN, ETHER EXTRACTED // DOSAGE AND ADMINISTRATION // [text follows] // PACKAGE INFORMATION // [text follows] // REFERENCES // [text follows] // 121 877800 //Parke, Davis & Co. // Detroit, Mi 48232 USA C-PD // A // Issued Aprile 1973 [French translation appears alongside English text throughout]"
Permanent Location
Storage Room 0010
0010-A
Condition Remarks
Box somewhat dirty, dented; no apparent problems wtih vial or leaflet
Copy Type
Original
Reference Types
Other
JPG
Reference Comments
See also 000.001.282; CD #8
Images
Less detail
Dates
1974
circa 1974
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001282 a-c
Description
Cylindrical glass vial (b) stopped with a rubber stopper and sealed with a metal cap around vial neck and lip; a plastic cap is attached to the metal cap such that when the plastic cap is pulled off, the seal on the metal cap is broken; vial is in a cardboard box (a) with a paper leaflet (c)
  1 image  
Accession Number
000001282 a-c
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Viral Vaccines
Vaccination
Influenza
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
Cylindrical glass vial (b) stopped with a rubber stopper and sealed with a metal cap around vial neck and lip; a plastic cap is attached to the metal cap such that when the plastic cap is pulled off, the seal on the metal cap is broken; vial is in a cardboard box (a) with a paper leaflet (c)
Number Of Parts
3
Part Names
a - box - Size: Length 5.7 cm x Width 2.9 cm x Depth 2.9 cm
b - vial - Size: Length 4.4 cm x Diam. 2.2 cm
c - leaflet (unfolded) - Size: Length 17.6 cm x Width 10.1 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Company
Site Made (City)
Detroit
Site Made (State)
Michigan
Site Made (Country)
United States of America
Dates
1974
circa 1974
Date Remarks
Based on expiry date
Material
glass: clear
paper: white; blue; black
cardboard: white; blue
plastic: blue
metal: silver
rubber: pink
Inscriptions
(a) Front: "5 ML. Bio. 1568 // FLUOGEN® // Standardized according to the U.S. Public // Health Service requirements for the // 1973-74 season. // Stock 4-1568-1-70 // PARKE-DAVIS"; bottom: "Preservative: 0.01% thimerosal (mercury deriv.) // Polysorbate 80, USP, added during manufacture. // U.S. Licence No. 1. Canadian Licence No. 1. // Store at temperature between 2° and 8° C. // (36° and 46° F.). // FREEZING DESTROYS POTENCY // Parke, Davis & Company // Detroit, Michigan 48232 U.S.A."; back: "5 ML. Bio. 1568 // INFLUENZA VIRUS VACCINE, BIVALENT // (IMMUNIZING ANTIGEN, ETHER EXTRACTED) // C Contains no less than 1000 CCA units per human dose (0.5 // ml.) in the recommended ratio of 700 CCA units of the A // influenza virus component representative of A/England/ // 42/72 (H3N2) and 300 CCA units of the B influenza virus // component representative of B/Massachusetts/1/71. // PARKE-DAVIS"; top: "USUAL ADULT DOSE – Two intramuscular injections // of 0.5 ml. each, given at least two months apart. See // package insert. // [dose repeated in French] // Prepared from formalin-stabilized, zonally-centrifuged // antigens, ether-extracted from virus propogated in the // extraembryonic fluid of the chick embryo. // U.S. Patent No. 3,105,012"; right side: "5 ML. Bio. 1568 // FLUOGEN // Parke, Davis & Co. // Exp. Date and Lot [printed] Nov. 15, 1974 // 903028C [stamped]"; (b) front: "C // 5 ML. Bio. 1568 // INFLUENZA VIRUS VACCINE, BIVALENT // (IMMUNIZING ANTIGEN, ETHER EXTRACTED) // FLUOGEN® // Contains no less than 1000 CCA units per human dose // (0.5 ml.) in the recommended ratio of 700 CCA units of the A influenza virus component representative of A/England/ // 42/72 (H3N2) and 300 CCA units of the B influenza virus // component representative of B/Massachusetts/1/71. // Parke, Davis & Co., Detroit, Mich. 48232 U.S.A."; back: "USUAL ADULT DOSE – Two // intramuscular injections of 0.5 // ml. each, given at least two months apart. See package // inssert. // Standardized according to the // U.S. Public Health Service // requirements for the 1973-74 // season. // U.S. Lic. No. 1. // Canadian Lic. No. 1. // Exp Date and Lot [printed] // Nov. 15, 1974 // 903028C [stamped]"; bottom: "W // 91 [embossed]"; top: "FLIP // OFF [embossed]"; (c) "C // FLUOGEN® // (INFLUENZA VIRUS VACCINE, BIVALENT) // IMMUNIZING ANTIGEN, ETHER EXTRACTED // PARKE-DAVIS // DESCRIPTION // [text follows] // 121 877800 C-PO // FLUOGEN // (INFLUENZA VIRUS VACCINE, BIVALENT) // IMMUNIZING ANTIGEN, ETHER EXTRACTED // [text continues from DESCRIPTION] // INDICATIONS // [text follows] // 121 877800 2 C - PD // FLUOGEN // (INFLUENZA VIRUS VACCINE, BIVALENT) // IMMUNIZING ANTIGEN, ETHER EXTRACTED // [text continues from INDICATIONS] // CONTRAINDICATIONS // [text follows] // PRECAUTIONS // [text follows] // ADVERSE REACTIONS // [text follows] // 121 877800 3 C-PD // FLUOGEN // (INFLUENZA VIRUS VACCINE, BIVALENT) // IMMUNIZING ANTIGEN, ETHER EXTRACTED // DOSAGE AND ADMINISTRATION // [text follows] // PACKAGE INFORMATION // [text follows] // REFERENCES // [text follows] // 121 877800 //Parke, Davis & Co. // Detroit, Mi 48232 USA C-PD // A // Issued Aprile 1973 [French translation appears alongside English text throughout]"
Permanent Location
Storage Room 0010
0010-A
Condition Remarks
Box somewhat dirty, dented; no apparent problems wtih vial or leaflet
Copy Type
Original
Reference Types
Other
JPG
Reference Comments
See also 000.001.281; CD #8
Images
Less detail
Dates
1983
circa 1983
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001287 a-c
Description
Acylindrical glass vial (b) stopped with a rubber stopper and sealed with a metal cap moulded over the vial neck and lip with a plastic cap that is attached to the metal cap such that when the plastic cap is removed, the seal on the metal cap is broken; vial is in a cardboard box (a) with a paper l…
  1 image  
Accession Number
000001287 a-c
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Viral Vaccines
Vaccination
Influenza
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
Acylindrical glass vial (b) stopped with a rubber stopper and sealed with a metal cap moulded over the vial neck and lip with a plastic cap that is attached to the metal cap such that when the plastic cap is removed, the seal on the metal cap is broken; vial is in a cardboard box (a) with a paper leaflet (c)
Number Of Parts
3
Part Names
a - box - Size: Length 5.7 cm x Width 2.9 cm x Depth 2.9 cm
b - vial - Size: Length 4.4 cm x Diam. 2.2 cm
c - leaflet (unfolded) - Size: Length 17.6 cm x Width 10.1 cm
Provenance
Collected by Parke-Davis
Maker
Parke-Davis Canada Inc.
Dates
1983
circa 1983
Date Remarks
Based on expiry date
Material
metal: silver
paper: white; blue; black
cardboard: white; blue; black
rubber: pink
glass: clear
plastic: blue
Inscriptions
(a) Front: "DIN 248991 // Fluogen* // Subvirion Vaccine // Influenza Virus Vaccine. // Trivalent, Types A and B // Dosage – Persons 13 years and older, // a single injection of 0.5 mL; persons // 3 years through 12 years, 2 injections // of 0.5 mL, 4 or more weeks apart; // persons 6 months through 35 months, // 2 injections of 0.25 mL, 4 or more // weeks apart. Inject intramuscularly. // See package insert. // 5 mL // PARKE-DAVIS"; right side: "Contains no less than 45 micrograms // of HA antigen content per 0.5 mL // dose in the recemmended ratio of 15 // µg of HA of the A influenza virus // component represen- // tative of A/Bangkok/1/79 (H3N2) // and 15 µg of HA of the B influenza // virus component representative of // B/Singapore/222/79. The vaccine is / of chick embryo origin. Polysorbate // 80 NF, added during manufacture. // Preservative: 0.01% thimerosal (mer- // cury derivative). Standardized accord- // ing to the 1982-83 NACI and US // PHS requirements. // *Reg. T.M. / M. Enr. Parke, Davis & Company // Parke-Davis Canada Inc. // auth. user / usager aut. // Can. Lic. No. 1 [printed] // (L) 26227 // Exp. JN 1983 [stamped]"; back: front repeated in French; left side: contents as printed on right side repeated in French; "Permis can. n° 1 // Parke-Davis Canada Inc. // Scarborough, Ontario // 266B670 26664"; top: "Store at temperature // between 2° and 8° C // (36° and 46° F) // Freezing destroys // potency. // [above 5 lines repeated in French] // 266B670 26664"; (b) front: "DIN 248991 // Fluogen* // Subvirion Vaccine // Influenza Virus Vaccine, // Trivalent, Types A and B // 5 mL // PARKE-DAVIS"; back: "(L) 26227 // EXP JN 1983 [stamped] // [contents, dosage and storage in English as on box] // Can. Lic. No. 1 // *Reg. T.M. Parke, Davis & Company // PARKE-DAVIS Canada Inc. auth. user // 266H130 26664"; bottom: "W // 37 [embossed]"; top: "FLIP // OFF [embossed]" (c) FLUOGEN* // INFLUENZA VIRUS VACCINE, TRIVALENT, TYPES A AND B // Subvirion Vaccine/Immunizing Antigen. // Ether Extracted // DESCRIPTION // [text follows] // CLINICAL PHARMACOLOGY // [text follows] // // 1 // [text continues from Clinical . . .] // INDICATIONS AND USAGE // [text follows] // CONTRAINDICATIONS // [text follows] // 2 // [text continues from Contraindications] // WARNING // [text follows] // PRECAUTIONS // [text follows] // PREGNANCY // [text follows] // ADVERSE REACTIONS // [text follows] // 3 // [text continues from Adverse . . .] // DOSAGE AND ADMINISTRATION // [text follows] // PACKAGE INFORMATION // [text follows] // REFERENCES // [text follows] // *Reg. T.M. / M. Enr. Parke, Davis & Company // Parke-Davis Canada Inc. auth. user / usager aut. // PARKE-DAVIS // 266E940 Parke-Davis Canada Inc., Scarborough, Ontario 26664 // 4 // [French translation occurs alongside English text throughout]"
Permanent Location
Storage Room 0010
0010-A3-5 Row G
Condition Remarks
Box somewhat dirty, dented; no apparent problems with vial or leaflet
Copy Type
Original
Reference Types
JPG
Reference Comments
CD #8
Images
Less detail
Dates
1973
circa 1973
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001468 a-b
Description
A cylindrical glass vial (b) inside a cardboard box (a); vial is stopped with a rubber stopper and sealed with a metal cap; a plastic cap covers the metal cap such that when it is pulled off it breaks the seal on the metal cap; vial has a paper label on front and sides and is full of liquid.
  5 images  
Accession Number
000001468 a-b
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Viral Vaccines
Vaccination
Influenza
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
A cylindrical glass vial (b) inside a cardboard box (a); vial is stopped with a rubber stopper and sealed with a metal cap; a plastic cap covers the metal cap such that when it is pulled off it breaks the seal on the metal cap; vial has a paper label on front and sides and is full of liquid.
Number Of Parts
2
Part Names
a - box - Size: Length 5.3 cm x Width 2.9 cm x Depth 2.9 cm
b - vial - Size: Length 4.4 cm x Diam. 2.2 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Co.
Site Made (City)
Detroit
Site Made (State)
Michigan
Site Made (Country)
United States of America
Dates
1973
circa 1973
Date Remarks
Based on expiry date
Material
paper: white; blue
plastic: blue
metal: silver
cardboard: blue; white
rubber: pink
glass: clear
Inscriptions
(a) Front: "5 ML. Bio. 1508 // FLUOGEN® // Standardized according to the U.S. Public // Health Service requirements for the // 1972-73 season. // PARKE-DAVIS"; top: "USUAL ADULT DOSE – Two intramuscular injec- // tions of 0.5 ml. each, given at least two months // apart. See package insert. // [dosage repeated in French] // Prepared from formalin stabilized, zonally cen- // trifuged antigens, ether-extracted from virus // propagated in the extraembryonic fluid of the // chick embryo. // U.S. Patent No. 3,105,012 // Polysorbate 80, U.S.P., added during // manufacture."; back: "5 ML. Bio, 1508 // INFLUENZA VIRUS VACCINE, BIVALENT // (IMMUNIZING ANTIGEN, ETHER EXTRACTED) // C // Contains 700 CCA units of A/Aichi/2/68/X-31 (H3N2) // strain (Hong Kong Variant) and 300 CCA units of // B/Massachusetts/1/71 strain in each 0.5-ml. dose. // Stock 4-1508-1-70 // PARKE-DAVIS"; bottom: "Contains 0.01% thimerosal (mercury derivative) // as a preservative. // U.S. Licence No. 1. // Canadian Licence No. 1. // Store at temperature between 2° and 8° C. (36° and 46° F.). // FREEZING DESTROYS POTENCY // SHAKE WELL BEFORE USING // Parke, Davis & Company // Detroit, Michigan 48232 // U.S.A. [printed] // XG YBY [handwritten over printed text]"; right side: "5 ML. Bio. 1508 // FLUOGEN // Parke, Davis & Co. // Exp. Date and Lot [printed] // Dec. 10, 1973 // 900259C [stamped]"; left side: "5 ML. Bio. 1508 // FLUOGEN // Parke, Davis & Co. // Stock 4-1508-1-70 [printed]"; (b) front: "C // 5 ML. Bio. 1508 // INFLUENZA VIRUS VACCINE, BIVALENT // (IMMUNIZING ANTIGEN, ETHER EXTRACTED) // FLUOGEN® // Contains 700 CCA units of A/Aichi/2/68/X-31 (H3N2) // strain (Hong Kong Variant) and 300 CCA units of // B/Massachusetts/1/71 strain in each 0.5-ml. dose. // Parke, Davis & Co., Detroit, Mich. 48232 U.S.A."; back: "USUAL ADULT DOSE–Two // intramuscular injections of 0.5 // ml. each, given at least two // months apart. See package // insert. // Standardized according to the // U.S. Public Health Service // requirements for the 1972-73 season. // U.S. Lic. No. 1. // Canadian Lic. No. 1 // Exp. Date and Lot [printed] // Dec. 10, 1973 // 900259C [stamped]"; bottom: "W // 103 [embossed]"; top: "FLIP // OFF [embossed]"
Permanent Location
Storage Room 0010
0010-A3-7 Row G
Condition Remarks
Box yellowing, dirty, scuffed, torn in two places on the bottom; no apparent problems with vial
Copy Type
Original
Reference Comments
CD #8
Images
Less detail
Dates
1965
circa 1965
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001469 a-c
Description
A cylindrical glass vial (b) inside a cardboard box (a) along with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded around the neck and lip; vial has a paper label on front and sides and is full of liquid.
  1 image  
Accession Number
000001469 a-c
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Viral Vaccines
Vaccination
Influenza
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
A cylindrical glass vial (b) inside a cardboard box (a) along with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded around the neck and lip; vial has a paper label on front and sides and is full of liquid.
Number Of Parts
3
Part Names
a - box - Size: Length 5.3 cm x Width 2.7 cm x Depth 2.7 cm
b - vial - Size: Length 4.2 cm x Diam. 2.3 cm
c - leaflet - Size: Length 17.6 cm x Width 10.0 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Co.
Site Made (City)
Detroit
Site Made (State)
Michigan
Site Made (Country)
United States of America
Dates
1965
circa 1965
Date Remarks
Based on expiry date
Material
paper: white; blue; cream
metal: silver
cardboard: blue; white; black
rubber: grey
glass: clear
Inscriptions
(a) Front: "5 CC. Bio. 666 // RESPROGEN® // Preservative: 0.01% thimerosal. // U.S.Lic. No. 1. Canadian Lic. No. 1. // PARKE, DAVIS & CO., DETROIT, MICH., U.S.A."; top: "An aluminum phosphate adsorbed combination of // Influenza Virus Vaccine, Polyvalent, Types A // and B, 600 CCA units per cc. including 200 CCA units per cc. of Asian strain, (prepared from re- // fined extra-embryonic fluid of the chick embryo // and killed by ultraviolet irradiation) and Adeno- // virus Vaccine (prepared from adenoviruses, // types 3 and 7 in approximately equal propor- // tions, grown in monkey kidney tissue cultures, // inactivated with formaldehyde and supplemen- // tal treatment with ultraviolet irradiation and // beta-propiolactone, as required, and refined by // adsorption on aluminumphosphate"; back: "5 CC. Bio. 666 // ADENOVIRUS AND INFLUENZA // VIRUS VACCINES, COMBINED, // ALUMINUM PHOSPHATE ADSORBED // C // Adenovirus Types 3 and 7 only. // Stock 4-666-1-70 // PARKE, DAVIS & CO. DETROIT, MICH., U.S.A."; bottom: "DOSAGE - Adults, two 1 cc. doses, given // intramuscularly, at least two months apart. // See circular. // SHAKE WELL BEFORE USING // Keep at 2° to 10° C. (35.6° to 50° F.). // FREEZING DESTROYS POTENCY // Expiration Date: [printed] JAN. 5, 1965 [stamped] // Lot No. [printed] 030103A {stamped]"; right side: "5 CC. Bio. 666 // RESPROGEN // Parke, Davis & Co. // Stock 4-666-1-70"; left side: identical to right side; (b) front: "5 CC. Bio. 666 // RESPROGEN® // (ADENOVIRUS AND INFLUENZA VIRUS // VACCINES, COMBINED, // ALUMINUM PHOSPHATE ADSORBED) // Adenovirus Types 3 and 7 only. // U.S. Lic. No. 1. Canadian Lic. No. 1. // PARKE, DAVIS & CO., DETROIT, MICH., U.S.A."; back: "SHAKE WELL // Dose–Adults, two // doses, 1 cc. each // at least two months apart. // See circular. // Exp. Date: [printed] // Jan. 5, 1965 [stamped] // Lot No. [printed] // 030103A [stamped]"; bottom: "K // 6 [embossed]" (c) "RESPROGEN®// (ADENOVIRUS AND INFLUENZA VIRUS VACCINES, // COMBINED, ALUMINUM PHOSPHATE ADSORBED) // [text follows] // ADMINISTRATION AND DOSAGE // [text follows] // BOOSTER OR RECALL DOSE // [text follows] // PRECAUTIONS // [text follows] // REACTIONS // [text follows] // DISCUSSION // [text follows] // STORAGE // [text follows] // PACKAGE INFORMATION // [text follows] // REFERENCES // [text follows] // PARKE, DAVIS [logo, see sketch on accession sheet] & COMPANY // DETROIT, MICHIGAN, U.S.A. // L-58-60 DD // Issued Apr. 1964"
Permanent Location
Storage Room 0010
0010-A3-5 Row G
Condition Remarks
Box yellowing, scuffed at edges; no apparent problems with vial or leaflet
Copy Type
Original
Reference Types
JPG
Reference Comments
CD #8
Images
Less detail

diphtheria-tetanus-pertussis vaccine

https://mhc.andornot.com/en/permalink/artifact4298
Dates
1956
circa 1956
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001472 a-c
Description
A cylindrical glass vial (b) inside a cardboard box (a) with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded over the neck and lip; vial has a paper label on front and sides and is half full of liquid; box has a round fluorescent orange sticker on the …
  5 images  
Accession Number
000001472 a-c
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Diphtheria Toxoid -- therapeutic use
Vaccination
Tetanus Toxoid -- therapeutic use
Pertussis Vaccine -- therapeutic use
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
A cylindrical glass vial (b) inside a cardboard box (a) with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded over the neck and lip; vial has a paper label on front and sides and is half full of liquid; box has a round fluorescent orange sticker on the right side and a rectangular white sticker on the bottom
Number Of Parts
3
Part Names
a - box - Size: Length 4.7 cm x Width 2.0 cm x Depth 2.2 cm
b - vial - Size: Length 3.5 cm x Diam. 1.7 cm
c - leaflet (unfolded) - Size: Length 15.3 cm x Width 11.0 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Co.
Site Made (City)
Detroit
Site Made (State)
Michigan
Site Made (Country)
United States of America
Dates
1956
circa 1956
Date Remarks
Based on expiry date
Material
paper: white; blue
ink: black; blue
metal: silver
cardboard: blue; white
rubber: pink
glass: clear
Inscriptions
(a) Front: "C 1.5 cc. Bio. 2091 // DIPHTHERIA - TETANUS - PERTUSSIS // ALUMINUM PHOSPHATE ADSORBED // TRIOGEN // Stock 4-2091-2 // PARKE, DAVIS & CO., DETROIT, MICH., U.S.A."; bottom: "Dosage – A complete immunizi [illeg.] // ment consists of 1.5 cc. div [illeg.] // three equal doses of 0.5 cc. each [illeg.] // at intervals of from four to six [illeg.] // See circular. // Contains 0.01% Thimeros [illeg.] // Keep at 2° to 10° C. (35° to [illeg.] // DO NOT FREEZE // SHAKE WELL BEFORE US [illeg.]"; back: "Indicated for prophylaxis against diph- // theria, tetanus and whooping cough. // U.S. Lic. No. 1 Canadian Lic. no. 1 // Expiration Date: [printed] APR-20-1956 [stamped] // Lot No. [printed] 027176 - H [stamped]"; top: "For One Complete Immunizing Treatment // DIPHTHERIA and TETANUS TOXOIDS // and PERTUSSIS VACCINE, COMBINED // ALUMINUM PHOSPHATE ADSORBED // Each 1.0 cc. contains 20,000 million killed // Phase 1 Hemophilus pertussis organisms of // proven antigenicity and adequate amounts // of Diphtheria and Tetanus Toxoids."; right side: "1.5 Bio. 2091 // [illeg.] - PERT. // Alu [illeg.] Phosphate Adsorbed. // TRIOGEN // Parke, Davis & Co."; left side: 1.5 cc. Bio. 2091 // DIPH. - TET. - PERT. // Aluminum Phosphate // Adsorbed // TRIOGEN // Parke, Davis & Co."; (b) front: "1.5 cc. Dose: 0.5 cc. Bio. 2091 // C DIPHTHERIA – TETANUS – PERTUSSIS // Aluminum Phosphate Adsorbed // TRIOGEN // Seecircular. // SHAKE WELL // U.S. License No. 1. [printed] // APR–201956 // 027176-H [stamped] // PARKE, DAVIS & CO., Detroit Mich., U.S.A. porinted]"; back: "1.0 cc. contains // 20,000 million H. // pertussis and ade- // quate Diphtheria and Tetanus // Toxoids."; bottom: "NSIA // O K // U.S.A. [embossed]"; (c) "DIPHTHERIA – TETANUS – PERTUSSIS // ALUMINUM PHOSPHATE ADSORBED // TRIOGEN // [text follows] // WHEN TO IMMUNIZE // [text follows] // DOSAGE // [text follows] // STERILIZATION OF SYRINGES AND NEEDLES // [text follows] // ADMINISTRATION // [text follows] // REACTIONS // [text follows] // RECALL OR STIMULATING DOSES // [text follows] // PACKAGES // [text follows] // REFERENCES // [text follows] // PARKE, DAVIS [logo, see sketch on accession sheet] & COMPANY // DETROIT, MICH., U.S.A. // K-67 // B-0548-F—1-15-54—50M"
Permanent Location
Storage Room 0010
0010-A3-5 Row H
Temporary Location
On display: "Vaccines and Immunization: Epidemics, Prevention, and Canadian Innovation"; Museum of Health Care, Nov. 28, 2013.
Condition Remarks
Box dented, dirty, scuffed, ink fading ; label on vial yellowing; no apparent problems with leaflet
Copy Type
Original
Reference Types
Book on internet
Reference Comments
https://books.google.ca/books?id=rfpT4uZW-D0C&printsec=frontcover#v=onepage&q&f=false
Research Facts
Triogen was later combined with the Salk polio vaccine to make Quadrigen, which proved to be toxic after experiencing temperature changes. The pertussis vaccine alone, as well as combined with those for diphtheria and tetanus, has long been controversial, and there have been cases in which it has allegedly made children very sick or caused their death.
Images
Less detail

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