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Physostigmine Sulphate hypodermic tablets

https://mhc.andornot.com/en/permalink/artifact4284
Dates
1905
circa 1905
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Other
Accession Number
000001458 a-e
Description
Two plastic tubes (c,d) stopped with corks inside a cardboard box in two pieces (a,b) separated by a sheet of cardboard folded to form a divider (e); the tubes have a paper labels on the front and on the corks, as does the box; the label on the box covers both lid and bottom and once served to hold…
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Accession Number
000001458 a-e
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, Other
MeSH Heading
Cholinergic Agents
Ophthalmology
Eye Diseases -- drug therapy
Description
Two plastic tubes (c,d) stopped with corks inside a cardboard box in two pieces (a,b) separated by a sheet of cardboard folded to form a divider (e); the tubes have a paper labels on the front and on the corks, as does the box; the label on the box covers both lid and bottom and once served to hold them together; it has since been torn open; tubes are full of tablets.
Number Of Parts
5
Part Names
a - box bottom - Size: Length 6.4 cm x Width 3.7 cm x Depth 1.2 cm
b - box top - Size: Length 3.4 cm x Width 3.7 cm x Depth 1.2 cm
c - tube - Size: Length 7.4 cm x Diam. 0.7 cm
d - tube - Size: Length 7.4 cm x Diam. 0.7 cm
e -divider (unfolded) - Size: Length 5.5 cm x Width 6.1 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Co.
Site Made (City)
Walkerville
Site Made (State)
Ontario
Site Made (Country)
Canada
Dates
1905
circa 1905
Date Remarks
Based on lot no.
Material
paper: cream; red; black
plastic: translucent yellow
cardboard: red; white; beige
cork: brown
Inscriptions
(b)Top: "MANUFACTURED BY // PARKE, DAVIS & CO. // WALKERVILLE, ONT."; (a,b) front: "100 HYPODERMATIC // TABLETS // No. 20 // Physostigmine // Sulphate // 1-100 GRAIN [printed] // C247245 [stamped] // PARKE, DAVIS & CO. // DETROIT, MICH. U.S.A. [printed]"; bottom: "[illeg.] TABLETS // [illeg.] 20 [printed] C 247245 [stamped] // [illeg.] sulplhate, 1-100 gr. // [illeg.] AVIS & CO. [printed]"; (c,d) front: "HYPODERMATIC TABLETS // No. 20 [printed] C 247245 [stamped] // Physostigmine sulphate, 1-100 gr. // PARKE, DAVIS & CO. [printed]"; top: "PARKE // DAVIS // & CO."
Permanent Location
Storage Room 0010
0010-A3-4 Row C
Condition Remarks
Box dirty and scuffed; labels yellowing; label on bottom of (a) half missing; labels on (c,d) and cardboard divider are yellowing
Copy Type
Original
Reference Types
Document
Reference Comments
https://www.drugbank.ca/drugs/DB00981 https://www.drugbank.ca/salts/DBSALT000243
Parke-Davis Lot Numbering System
Research Facts
Physostigmine is a cholinesterase inhibitor, which blocks neurotransmitters in the nervous system; can cross membranes such as the blood-brain barrier, so it can treat the central nervous system.
Images
Less detail