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diphtheria-tetanus-pertussis vaccine

https://mhc.andornot.com/en/permalink/artifact4298
Dates
1956
circa 1956
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001472 a-c
Description
A cylindrical glass vial (b) inside a cardboard box (a) with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded over the neck and lip; vial has a paper label on front and sides and is half full of liquid; box has a round fluorescent orange sticker on the …
  5 images  
Accession Number
000001472 a-c
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Diphtheria Toxoid -- therapeutic use
Vaccination
Tetanus Toxoid -- therapeutic use
Pertussis Vaccine -- therapeutic use
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
A cylindrical glass vial (b) inside a cardboard box (a) with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded over the neck and lip; vial has a paper label on front and sides and is half full of liquid; box has a round fluorescent orange sticker on the right side and a rectangular white sticker on the bottom
Number Of Parts
3
Part Names
a - box - Size: Length 4.7 cm x Width 2.0 cm x Depth 2.2 cm
b - vial - Size: Length 3.5 cm x Diam. 1.7 cm
c - leaflet (unfolded) - Size: Length 15.3 cm x Width 11.0 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Co.
Site Made (City)
Detroit
Site Made (State)
Michigan
Site Made (Country)
United States of America
Dates
1956
circa 1956
Date Remarks
Based on expiry date
Material
paper: white; blue
ink: black; blue
metal: silver
cardboard: blue; white
rubber: pink
glass: clear
Inscriptions
(a) Front: "C 1.5 cc. Bio. 2091 // DIPHTHERIA - TETANUS - PERTUSSIS // ALUMINUM PHOSPHATE ADSORBED // TRIOGEN // Stock 4-2091-2 // PARKE, DAVIS & CO., DETROIT, MICH., U.S.A."; bottom: "Dosage – A complete immunizi [illeg.] // ment consists of 1.5 cc. div [illeg.] // three equal doses of 0.5 cc. each [illeg.] // at intervals of from four to six [illeg.] // See circular. // Contains 0.01% Thimeros [illeg.] // Keep at 2° to 10° C. (35° to [illeg.] // DO NOT FREEZE // SHAKE WELL BEFORE US [illeg.]"; back: "Indicated for prophylaxis against diph- // theria, tetanus and whooping cough. // U.S. Lic. No. 1 Canadian Lic. no. 1 // Expiration Date: [printed] APR-20-1956 [stamped] // Lot No. [printed] 027176 - H [stamped]"; top: "For One Complete Immunizing Treatment // DIPHTHERIA and TETANUS TOXOIDS // and PERTUSSIS VACCINE, COMBINED // ALUMINUM PHOSPHATE ADSORBED // Each 1.0 cc. contains 20,000 million killed // Phase 1 Hemophilus pertussis organisms of // proven antigenicity and adequate amounts // of Diphtheria and Tetanus Toxoids."; right side: "1.5 Bio. 2091 // [illeg.] - PERT. // Alu [illeg.] Phosphate Adsorbed. // TRIOGEN // Parke, Davis & Co."; left side: 1.5 cc. Bio. 2091 // DIPH. - TET. - PERT. // Aluminum Phosphate // Adsorbed // TRIOGEN // Parke, Davis & Co."; (b) front: "1.5 cc. Dose: 0.5 cc. Bio. 2091 // C DIPHTHERIA – TETANUS – PERTUSSIS // Aluminum Phosphate Adsorbed // TRIOGEN // Seecircular. // SHAKE WELL // U.S. License No. 1. [printed] // APR–201956 // 027176-H [stamped] // PARKE, DAVIS & CO., Detroit Mich., U.S.A. porinted]"; back: "1.0 cc. contains // 20,000 million H. // pertussis and ade- // quate Diphtheria and Tetanus // Toxoids."; bottom: "NSIA // O K // U.S.A. [embossed]"; (c) "DIPHTHERIA – TETANUS – PERTUSSIS // ALUMINUM PHOSPHATE ADSORBED // TRIOGEN // [text follows] // WHEN TO IMMUNIZE // [text follows] // DOSAGE // [text follows] // STERILIZATION OF SYRINGES AND NEEDLES // [text follows] // ADMINISTRATION // [text follows] // REACTIONS // [text follows] // RECALL OR STIMULATING DOSES // [text follows] // PACKAGES // [text follows] // REFERENCES // [text follows] // PARKE, DAVIS [logo, see sketch on accession sheet] & COMPANY // DETROIT, MICH., U.S.A. // K-67 // B-0548-F—1-15-54—50M"
Permanent Location
Storage Room 0010
0010-A3-5 Row H
Temporary Location
On display: "Vaccines and Immunization: Epidemics, Prevention, and Canadian Innovation"; Museum of Health Care, Nov. 28, 2013.
Condition Remarks
Box dented, dirty, scuffed, ink fading ; label on vial yellowing; no apparent problems with leaflet
Copy Type
Original
Reference Types
Book on internet
Reference Comments
https://books.google.ca/books?id=rfpT4uZW-D0C&printsec=frontcover#v=onepage&q&f=false
Research Facts
Triogen was later combined with the Salk polio vaccine to make Quadrigen, which proved to be toxic after experiencing temperature changes. The pertussis vaccine alone, as well as combined with those for diphtheria and tetanus, has long been controversial, and there have been cases in which it has allegedly made children very sick or caused their death.
Images
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wax model, adenomyoma of uterus

https://mhc.andornot.com/en/permalink/artifact312
Dates
1940
circa 1940
Collection
Dr. Robertson / Marjorie Winslow Collection
Category
Basic Science Artifacts
Classification
Basic Science, Anatomy
Accession Number
996003032 a-c
Description
Wax models (moulage) of adenomyoma of the uterus and a follicular cyst and a thick-walled corpus luteum cyst in the ovary on the left side; the right side shows a normal fallopian tube and ovary; the models are made of oil-painted beeswax with talc, built up on a plywood base with gauze and wire fo…
  5 images  
Accession Number
996003032 a-c
Author
Marjorie Winslow
Collection
Dr. Robertson / Marjorie Winslow Collection
Category
Basic Science Artifacts
Classification
Basic Science, Anatomy
MeSH Heading
Adenomyoma -- models
Uterus -- models
Uterine Diseases -- models
Follicular Cyst -- models
Ovarian Cysts -- models
Ovary -- models
Gynecology -- models
Models, Anatomic
MM= Teaching Materials -- models
Description
Wax models (moulage) of adenomyoma of the uterus and a follicular cyst and a thick-walled corpus
luteum cyst in the ovary on the left side; the right side shows a normal fallopian tube and ovary;
the models are made of oil-painted beeswax with talc, built up on a plywood base with gauze and
wire for extra support; (b,c) are made of wax only; (a) the model shows a uterus split open to
show a lesion of the thickening of the uterine endometrium walls; red spots indicate hemorrhaging;
the left side of the model shows an ovary enlarged and distended with a follicular cyst and
a corpus luteal cyst; the right side of the model shows a normal fallopian tube and ovary; (b)
shows a cross-section of the follicular cyst and the corpus luteal cyst seen in (a); (c) shows
a cross-section of the normal fallopian tube and ovary seen in (a); the red spot in the ovary
likely indicates a small normal follicle rupture which has not completely healed; the models are
painted to depict true colour
Number Of Parts
3
Part Names
a - model, anatomical: adenomyoma of uterus - Size: Length 19.8 cm. x Width 10.8 cm. x Depth 4.2 cm.
b - model, anatomical: cross-section of ovarian follicular cyst - Size: Length 3.4 cm. x Width 2.9 cm. x Depth 1.2 cm.
c - model, anatomical: cross-section of thick-walled corpus luteum cyst - Size: Length 6.8 cm. x Width 5.0 cm. x Depth 1.1 cm.
Provenance
Models made by Marjorie Winslow; they were commissioned by Dr. Robertson, who also helped with
anatomical details
Maker
Marjorie Winslow
Site Made (City)
Kingston
Site Made (State)
Ontario
Site Made (Country)
Canada
Dates
1940
circa 1940
Date Remarks
Models made between 1940-1945
Material
beeswax with talc: cream
oil paints: flesh tone; red; blue; yellow
wood: beige
fabric: white
metal: dark grey
Inscriptions
(a) the number "106" is written in red on the bottom of the plywood support
Permanent Location
Storage Room 0010
0010-G2-Box 4
Condition Remarks
(a) There are no chips or breaks in the wax; there is a small crack in the front central part;
the surface is undamaged; (b,c) the models show no chips, cracks or breaks in the wax; the surfaces
are undamaged
Copy Type
Original
Reference Types
Person
Document
JPG
Reference Comments
Model subject identified by Dr. J.A. Low; model-making techniques described by Marjorie Winslow
in an oral interview (transcribed); CD #9
Research Facts
See transcribed oral interview; the cause of adenomyoma is unsure; the fallopian tubes and ovaries
indicate that the patient is post-menopausal
Images
Less detail