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diphtheria-tetanus-pertussis vaccine

https://mhc.andornot.com/en/permalink/artifact4298
Dates
1956
circa 1956
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
Accession Number
000001472 a-c
Description
A cylindrical glass vial (b) inside a cardboard box (a) with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded over the neck and lip; vial has a paper label on front and sides and is half full of liquid; box has a round fluorescent orange sticker on the …
  5 images  
Accession Number
000001472 a-c
Collection
Parke-Davis Collection
Category
Pharmacy and Drug Artifacts
Vaccination
Classification
Pharmacy, Infectious Diseases
Vaccination
MeSH Heading
Diphtheria Toxoid -- therapeutic use
Vaccination
Tetanus Toxoid -- therapeutic use
Pertussis Vaccine -- therapeutic use
MM= Drugs -- vaccines -- container
MM= Drug Packaging -- container -- vial
Description
A cylindrical glass vial (b) inside a cardboard box (a) with a paper leaflet (c); vial is stopped with a rubber stopper and sealed with a metal cap moulded over the neck and lip; vial has a paper label on front and sides and is half full of liquid; box has a round fluorescent orange sticker on the right side and a rectangular white sticker on the bottom
Number Of Parts
3
Part Names
a - box - Size: Length 4.7 cm x Width 2.0 cm x Depth 2.2 cm
b - vial - Size: Length 3.5 cm x Diam. 1.7 cm
c - leaflet (unfolded) - Size: Length 15.3 cm x Width 11.0 cm
Provenance
Collected by Parke-Davis
Maker
Parke, Davis & Co.
Site Made (City)
Detroit
Site Made (State)
Michigan
Site Made (Country)
United States of America
Dates
1956
circa 1956
Date Remarks
Based on expiry date
Material
paper: white; blue
ink: black; blue
metal: silver
cardboard: blue; white
rubber: pink
glass: clear
Inscriptions
(a) Front: "C 1.5 cc. Bio. 2091 // DIPHTHERIA - TETANUS - PERTUSSIS // ALUMINUM PHOSPHATE ADSORBED // TRIOGEN // Stock 4-2091-2 // PARKE, DAVIS & CO., DETROIT, MICH., U.S.A."; bottom: "Dosage – A complete immunizi [illeg.] // ment consists of 1.5 cc. div [illeg.] // three equal doses of 0.5 cc. each [illeg.] // at intervals of from four to six [illeg.] // See circular. // Contains 0.01% Thimeros [illeg.] // Keep at 2° to 10° C. (35° to [illeg.] // DO NOT FREEZE // SHAKE WELL BEFORE US [illeg.]"; back: "Indicated for prophylaxis against diph- // theria, tetanus and whooping cough. // U.S. Lic. No. 1 Canadian Lic. no. 1 // Expiration Date: [printed] APR-20-1956 [stamped] // Lot No. [printed] 027176 - H [stamped]"; top: "For One Complete Immunizing Treatment // DIPHTHERIA and TETANUS TOXOIDS // and PERTUSSIS VACCINE, COMBINED // ALUMINUM PHOSPHATE ADSORBED // Each 1.0 cc. contains 20,000 million killed // Phase 1 Hemophilus pertussis organisms of // proven antigenicity and adequate amounts // of Diphtheria and Tetanus Toxoids."; right side: "1.5 Bio. 2091 // [illeg.] - PERT. // Alu [illeg.] Phosphate Adsorbed. // TRIOGEN // Parke, Davis & Co."; left side: 1.5 cc. Bio. 2091 // DIPH. - TET. - PERT. // Aluminum Phosphate // Adsorbed // TRIOGEN // Parke, Davis & Co."; (b) front: "1.5 cc. Dose: 0.5 cc. Bio. 2091 // C DIPHTHERIA – TETANUS – PERTUSSIS // Aluminum Phosphate Adsorbed // TRIOGEN // Seecircular. // SHAKE WELL // U.S. License No. 1. [printed] // APR–201956 // 027176-H [stamped] // PARKE, DAVIS & CO., Detroit Mich., U.S.A. porinted]"; back: "1.0 cc. contains // 20,000 million H. // pertussis and ade- // quate Diphtheria and Tetanus // Toxoids."; bottom: "NSIA // O K // U.S.A. [embossed]"; (c) "DIPHTHERIA – TETANUS – PERTUSSIS // ALUMINUM PHOSPHATE ADSORBED // TRIOGEN // [text follows] // WHEN TO IMMUNIZE // [text follows] // DOSAGE // [text follows] // STERILIZATION OF SYRINGES AND NEEDLES // [text follows] // ADMINISTRATION // [text follows] // REACTIONS // [text follows] // RECALL OR STIMULATING DOSES // [text follows] // PACKAGES // [text follows] // REFERENCES // [text follows] // PARKE, DAVIS [logo, see sketch on accession sheet] & COMPANY // DETROIT, MICH., U.S.A. // K-67 // B-0548-F—1-15-54—50M"
Permanent Location
Storage Room 0010
0010-A3-5 Row H
Temporary Location
On display: "Vaccines and Immunization: Epidemics, Prevention, and Canadian Innovation"; Museum of Health Care, Nov. 28, 2013.
Condition Remarks
Box dented, dirty, scuffed, ink fading ; label on vial yellowing; no apparent problems with leaflet
Copy Type
Original
Reference Types
Book on internet
Reference Comments
https://books.google.ca/books?id=rfpT4uZW-D0C&printsec=frontcover#v=onepage&q&f=false
Research Facts
Triogen was later combined with the Salk polio vaccine to make Quadrigen, which proved to be toxic after experiencing temperature changes. The pertussis vaccine alone, as well as combined with those for diphtheria and tetanus, has long been controversial, and there have been cases in which it has allegedly made children very sick or caused their death.
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suppository mould

https://mhc.andornot.com/en/permalink/artifact5430
Dates
1900
1930
circa 1900-1930
Collection
University Health Network - Academy of Medicine Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, General
Accession Number
1934.8.9
Description
Brass suppository mould, composed of three hinged pieces.
  1 image  
Accession Number
1934.8.9
Collection
University Health Network - Academy of Medicine Collection
Category
Pharmacy and Drug Artifacts
Classification
Pharmacy, General
MeSH Heading
Drug Compounding
Administration, Rectal, Suppositories
Description
Brass suppository mould, composed of three hinged pieces.
Number Of Parts
1
Provenance
Acquired from the Academy of Medicine; donated by Dr. W.H. Brydon of Brampton, Ont; owned and used by Dr. Charles Robinson.
Site Made (Country)
Canada
Dates
1900
1930
circa 1900-1930
Date Remarks
Original record had "early 20c"
Material
metal: brownish-grey
Inscriptions
Inscribed with a "4"
Permanent Location
Storage Room 0010
0010-A
Dimension Notes
Length 12.2 cm x Width 2.5 cm x Depth 2.5 cm
Copy Type
Original
Reference Types
JPG
Reference Comments
CD #UHN
Research Facts
The hinged catch secures and holds the mould together; makes 12 suppositories.
Images
Less detail