Empty bottle of liquid inhalation anaesthetic Penthrane; consists of (a) an amber glass cylindrical bottle with a flat bottom, short threaded neck and rounded lip; green label with white text; the top of the bottle is covered with (b) a round plastic lid which is threaded inside, has a series of ve…
Empty bottle of liquid inhalation anaesthetic Penthrane; consists of (a) an amber glass cylindrical bottle with a flat bottom, short threaded neck and rounded lip; green label with white text; the top of the bottle is covered with (b) a round plastic lid which is threaded inside, has a series of vertical lines on the sides and a manufacturer's logo on the top; closure loose..
Number Of Parts
2
Part Names
a - Penthrane bottle - Size: Length 11.3 cm. x Diameter4.9 cm.
Abbott Laboratories manufactured methoxyflurane, sold under the brand name Penthrane, from 1961 to 2001. A fluorinated ether, methoxyflurane was first synthesized in 1958 by Dow Chemical Company. It was one of several compounds investigated by anesthesiologists Joseph F. Artusio, Jr., M.D. (1917-2011) and Alan Van Poznak, M.D. (b. 1927). They published their research into the clinical use of methoxyflurane in 1960. A number of other positive reports quickly followed and it seemed that methoxyflurane was a perfect inhalation anesthetic: nonexplosive and nonflammable with fast induction and recovery times and few adverse effects. It has also been used for analgesia (pain relief), in such products as Abbott's Analgizer, a self-administration inhaler. Studies showing its potential kidney and liver toxicity caused methoxyflurane to fall out of favor in the United States by the late 1970s.
Exhibit History
On display, Queen's University Department of Medicine third floor, August 20, 2013.