Hardcover book with dust jacket about the discovery of the drug Heparin and its effect on open heart surgery; first page with handwriting in black pen is acknowledgement note from the author to Morley Cohen; divided into a list of pervious books, author's introduction, introduction, and four sectio…
Hardcover book with dust jacket about the discovery of the drug Heparin and its effect on open heart surgery; first page with handwriting in black pen is acknowledgement note from the author to Morley Cohen; divided into a list of pervious books, author's introduction, introduction, and four sections of content; 205 pages; on the back cover there is another brief description of the book and the author; the back cover also folds into the book and on this fold is a small biography and picture of W. G. (Bill) Bigalow.
Number Of Parts
1
Provenance
Laurie Lam is a book dealer who came into possession of several items from the library of cardiac pioneer, Morley Cohen. The book was initially put up on the internet for sale.
On the front dust jacket: "A Renowned Heart Surgeon // on Canada's Role in One // of the Greatest Medical // Breakthroughs of the Century // MYSTERIOUS HEPARIN // THE KEY TO OPEN HEART SURGERY // W. G. BIGELOW"; on the inside page: "MYSTERIOUS // HEPARIN // THE KEY TO // OPEN HEART SURGERY // To Morley Cohen - who played // an integral role in the // development of open // heart surgery. // With warm regards // Bill Bigelow"; "p a r t 1 // DISCOVERY AND DEVELOPMENT OF HEPARIN // p a r t 2 // THE USE OF HEPARIN IN BLOOD // COAGULATION DISEASES // p a r t 3 // THE USE OF HEPARIN IN HEART AND LUNG SURGERY // p a r t 4 // EACH END A NEW BEGINNING"
Permanent Location
Storage Room 2005
Length
23.5 cm
Width
15.7 cm
Depth
1.8 cm
Unit Of Measure
centimeters
Dimension Notes
Length 23.5 cm x Width 15.7 cm x Depth 1.8 cm
Condition Remarks
Almost excellent, but the cover is slightly bent at the top on the front and back sides
Copy Type
original
Reference Types
Internet
Reference Comments
Wikipedia
Research Facts
Heparin, also known as unfractionated heparin (UFH), is a medication which is used as an anticoagulant (blood thinner). Specifically it is used to treat and prevent deep vein thrombosis, pulmonary embolism, and arterial thromboembolism. It is also used in the treatment of heart attacks and unstable angina. It is given by injection into a vein.[3] Other uses include inside test tubes and kidney dialysis machines.
Common side effects include bleeding, pain at the injection site, and low blood platelets. Serious side effects include heparin induced thrombocytopenia. Greater care is needed in those with poor kidney function. Heparin appears to be relatively safe for use during pregnancy and breastfeeding. Heparin is a naturally occurring glycosaminoglycan.
The discovery of heparin was announced in 1916. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world, when used for prevention, is about 9.63 to 37.95 USD per month. In the United States it costs about 25 to 50 USD per month. A fractionated version of heparin, known as low molecular weight heparin, is also available.